Therefore, these drugs are com-biniruyut with thiazides, or loop tiazidopodobnymi diuretics. Diuretics combined with many antihypertensive drugs for at-tentsirovaniya their actions and reduce the side effects. In addition to hypertension, captopril use in chronic heart failure. Insufficient heart begins to contract more efficiently - cardiac output increases. Edema may develop heart failure, kidney disease, and several other pathological conditions. With increasing content of Na + ions in vascular here muscle is broken funktsiyaNa + / Ca2 + exchanger (Na + input 3 and output 1 Ca2 +): Na + ions outside estimate cell, and ions Ca2 + is not out of Atrial Premature Contraction cells. Reducing the level of Ca2 + in cytoplasm of smooth muscle fibers leading to muscle relaxation and increased vascular Niya. Losartan and valsartan is used for the systematic treatment of hypertension, especially in hypersensitive ACE inhibitors. Dihydropyridines to reduce tachycardia combined with ? adrenobloka-tori, ACE inhibitors to reduce estimate - with thiazide diuretics. In chronic congestive heart failure, ACE inhibitors, Ras shiryaya arterial and venous vessels, reduce the respectively afterload and preload on the heart. In Further the volume of blood plasma is restored and blood pressure is reduced by increasing the blood vessels. However, more often they are combined with other means, lowers blood pressure. To quickly lower blood pressure used furosemide (Lasix) for long-term systematic treatment - hydrochlorothiazide (dihlotiazid, gipotiazid), chlorthalidone (oksodolin, gigroton), etc. Other drugs in this group - candesartan, irbesartan, telmisartan here offer similar to the properties of losartan. Duration of action 24 hours Enalaprilat hypertension administered intravenously. Action of estimate II due to its effect on the angiotensin receptor-ry, which is designated as AT1-receptors and AT2-receptors. moexipril. Duration of action 6-8 hours for a more rapid reduction in blood pressure (for non-severe hypertensive crises) drug use sublinear gvalno. As antihypertensive agents diuretics prescribed regularly in small doses, usually 1 time per day for excretion of excess Na +. By vasopeptidase include ACE and neutral endopeptidase, which inactivates-viruet atrial natriuretic peptide. Losartan (Cozaar), valsartan prevented the action of angiotensin II on AT1-receptors vascular sympathetic innervation and cortical adrenals. As well as ACE inhibitors, angiotensin AT1receptors Polycythemia rubra vera cause hyperkalemia. Captopril (Capoten, tenziomin) appointed interior. The frequency of contractions of the heart with little change. Of particular interest estimate omapatrilat, which inhibits and neutral endopeptidase and ACE. Unlike ACE inhibitors estimate blockers do not affect the Uro-Wen bradykinin and cause fewer side effects. That is exactly what are diuretics, used for edema. Enalapril (renitek) - prodrug, is well absorbed in zheludochnokishech Mr tract; becomes active enalaprilat. When hypertensive crises due to the risk of stroke, use of hypothetical zivnye tools that provide quick hypotensive effect. Na + ions osmotically highly active, the osmotic pressure in interstitial fluid is mainly determined by ion estimate of Na +.
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